Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835552 | 0.85 | PPARG (0.47) | L3MBTL1PPARGPPARAS1PR1ALDH1A1 | |
| SCHEMBL11826787 | 0.85 | ALDH1A1 (0.47) | TDP1L3MBTL1PPARGPPARATAAR1 | |
| SCHEMBL27808300 | 0.83 | ANPEP (0.43) | PPARGPPARAALDH1A1 | |
| SCHEMBL9492547 | 0.83 | PPARG (0.51) | FFAR1PPARGPPARATAAR1 | |
| SCHEMBL3433828 | 0.82 | PPARG (0.50) | TDP1PPARGPPARACYP1A2SMN1; SMN2 | |
| SCHEMBL7372199 | 0.82 | PPARG (0.50) | TDP1PPARGPPARACYP1A2SMN1; SMN2 | |
| SCHEMBL11823101 | 0.82 | PTGS2 (0.54) | — | |
| SCHEMBL11828893 | 0.82 | ALDH1A1 (0.61) | S1PR1S1PR5SMN1; SMN2ALDH1A1 | |
| SCHEMBL11837707 | 0.82 | ALDH1A1 (0.47) | L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12400797 | 0.81 | FFAR1 (0.47) | FFAR1TDP1L3MBTL1DPP4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |