Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15619830 | 0.89 | LMNA (0.45) | CES2CES1ALDH1A1TSHRPEPD | |
| SCHEMBL7719291 | 0.87 | PLG (0.36) | CES2CES1HTTKMT2AHPGD | |
| SCHEMBL13705727 | 0.86 | SMN1; SMN2 (0.38) | CES2CES1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL8156241 | 0.84 | — | — | |
| SCHEMBL13282650 | 0.84 | — | — | |
| SCHEMBL3991168 | 0.84 | ALDH1A1 (0.47) | CES2CES1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL8536055 | 0.82 | ALDH1A1 (0.50) | CES2CES1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL2400052 | 0.82 | ALDH1A1 (0.50) | CES2CES1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL1987532 | 0.82 | ALDH1A1 (0.48) | CES2CES1HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL15130223 | 0.82 | ALOX15 (0.33) | CES2CES1ALDH1A1PEPDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387885-B1 | HORMONE INHIBITORS; CONTRACEPTIVES | ABBOTT LABORATORIES | 2002-05-14 | — | — | US | disclosed |
| WO-2000012521-A1 | 3', 3'-N-BIS-DESMETHYL-3'-N-CYCLOALKYL ERYTHROMYCIN DERIVATIVES AS LHRH ANTAGONISTS | ABBOTT LABORATORIES (US) | 2000-03-09 | — | — | WO | disclosed |