Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578224 | 0.82 | TBXAS1 (0.64) | TBXAS1CYP4F2CYP4A11SMN1; SMN2MEN1 | |
| SCHEMBL7714709 | 0.81 | TBXAS1 (0.50) | TBXAS1CYP4F2CYP4A11SMN1; SMN2MEN1 | |
| SCHEMBL7714707 | 0.81 | TBXAS1 (0.50) | TBXAS1CYP4F2CYP4A11SMN1; SMN2MEN1 | |
| SCHEMBL7714820 | 0.78 | TBXAS1 (0.48) | TBXAS1CYP4F2CYP4A11SMN1; SMN2MEN1 | |
| SCHEMBL20556929 | 0.74 | ELANE (0.41) | MEN1KMT2ANPC1TSHRAKT1 | |
| SCHEMBL20556926 | 0.74 | ELANE (0.41) | MEN1KMT2ANPC1TSHRAKT1 | |
| SCHEMBL20556925 | 0.74 | ELANE (0.41) | MEN1KMT2ANPC1TSHRAKT1 | |
| SCHEMBL27517126 | 0.73 | MEN1 (0.54) | TBXAS1CYP4F2CYP4A11SMN1; SMN2MEN1 | |
| Succinic Acid Diethyl Ester SCHEMBL28851670 | 0.73 | SMN1; SMN2 (0.58) | TBXAS1CYP4F2CYP4A11SMN1; SMN2MEN1 | |
| SCHEMBL21119502 | 0.72 | KMT2A (0.44) | SMN1; SMN2KMT2AL3MBTL1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |