Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7714707 | 1.00 | TBXAS1 (0.50) | TBXAS1SMN1; SMN2CYP4F2CYP4A11MEN1 | |
| SCHEMBL2242761 | 0.88 | TRPV1 (0.49) | TBXAS1SMN1; SMN2CYP4F2CYP4A11MEN1 | |
| SCHEMBL2242758 | 0.88 | TRPV1 (0.49) | TBXAS1SMN1; SMN2CYP4F2CYP4A11MEN1 | |
| SCHEMBL14578224 | 0.86 | TBXAS1 (0.64) | TBXAS1SMN1; SMN2CYP4F2CYP4A11MEN1 | |
| SCHEMBL28715373 | 0.84 | MEN1 (0.47) | TBXAS1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL28719331 | 0.84 | MEN1 (0.47) | TBXAS1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL27820228 | 0.82 | CYP4F2 (0.43) | TBXAS1CYP4F2CYP4A11TRPV1 | |
| SCHEMBL7714820 | 0.82 | TBXAS1 (0.48) | TBXAS1SMN1; SMN2CYP4F2CYP4A11MEN1 | |
| SCHEMBL7714815 | 0.81 | TBXAS1 (0.47) | TBXAS1SMN1; SMN2CYP4F2CYP4A11MEN1 | |
| SCHEMBL11808129 | 0.80 | TBXAS1 (0.48) | TBXAS1L3MBTL1MAPTAKT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |