Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14578224 | 0.83 | TBXAS1 (0.64) | TBXAS1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7714709 | 0.82 | TBXAS1 (0.50) | TBXAS1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7714707 | 0.82 | TBXAS1 (0.50) | TBXAS1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL31520407 | 0.81 | CES2 (0.47) | TBXAS1SMN1; SMN2AKT1CES2CES1 | |
| SCHEMBL11309145 | 0.81 | SMN1; SMN2 (0.49) | TBXAS1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11309141 | 0.81 | SMN1; SMN2 (0.49) | TBXAS1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18801487 | 0.79 | CYP1A2 (0.47) | TBXAS1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9068456 | 0.79 | CYP1A2 (0.47) | TBXAS1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7714815 | 0.78 | TBXAS1 (0.47) | TBXAS1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL16728116 | 0.77 | MAPT (0.51) | MEN1KMT2AMAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |