Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712683 | 0.91 | TSHR (0.47) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL29433567 | 0.91 | TSHR (0.47) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL7378104 | 0.83 | CA12 (0.48) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL3567927 | 0.83 | TSHR (0.49) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL3567925 | 0.82 | TSHR (0.47) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL7383220 | 0.81 | TSHR (0.44) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL6756729 | 0.76 | MAOA (0.46) | TSHRALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL25060076 | 0.75 | MAPT (0.42) | TSHRALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL7714706 | 0.75 | TSHR (0.44) | TSHRALDH1A1KDM4EHSD17B10CA12 | |
| SCHEMBL8091366 | 0.75 | NOTUM (0.43) | TSHRALDH1A1KDM4EL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369110-B1 | PROPHYLACTIC AGENT FOR DISEASES CAUSED BY THE ACCELERATION OF THE SODIUM/PROTON EXCHANGE TRANSPORT SYSTEM | SUMITOMO PHARMACEUTICALS COMPANY (JP) | 2002-04-09 | — | — | US | disclosed |
| EP-1083166-A1 | NOVEL SUBSTITUTED GUANIDINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-03-14 | — | — | EP | disclosed |