Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31090834 | 0.90 | CA12 (0.50) | CA12CA9TRPA1TSHRL3MBTL1 | |
| SCHEMBL7911204 | 0.90 | CA12 (0.50) | CA12CA9TRPA1TSHRL3MBTL1 | |
| SCHEMBL7714827 | 0.83 | TSHR (0.45) | CA12CA9TSHRL3MBTL1KDM4E | |
| SCHEMBL5600204 | 0.81 | CA12 (0.59) | CA12CA9TRPA1ALOX15 | |
| SCHEMBL29476751 | 0.81 | CA12 (0.59) | CA12CA9TRPA1ALOX15 | |
| SCHEMBL7216486 | 0.80 | CA12 (0.41) | CA12CA9L3MBTL1ALDH1A1POLB | |
| SCHEMBL6756729 | 0.80 | MAOA (0.46) | TSHRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7218351 | 0.79 | CA12 (0.52) | CA12CA9L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL5204894 | 0.79 | NR4A2 (0.37) | CA12CA9L3MBTL1ALDH1A1MAPT | |
| SCHEMBL7712649 | 0.77 | RAB9A (0.46) | CA12CA9TSHRL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998055475-A1 | GUANIDINE DERIVIATIVES AS INHIBITORS OF NA+/H+ EXCHANGE IN CELLS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |