Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101638 | 0.86 | NQO2 (0.51) | RXFP1TRPV1GAAPOLBALDH1A1 | |
| SCHEMBL7715176 | 0.82 | CASP6 (0.40) | TRPV1GAAPOLBALDH1A1HPGD | |
| SCHEMBL487254 | 0.76 | TRPV1 (0.64) | TRPV1MEN1KMT2ANQO2KDM4E | |
| SCHEMBL31680675 | 0.76 | TRPV1 (0.64) | TRPV1MEN1KMT2ANQO2KDM4E | |
| SCHEMBL25631112 | 0.74 | POLB (0.52) | RXFP1TRPV1GAAPOLBALDH1A1 | |
| SCHEMBL9156203 | 0.74 | CASP6 (0.64) | RXFP1TRPV1GAAPOLBALDH1A1 | |
| SCHEMBL11876012 | 0.73 | RXFP1 (0.53) | RXFP1TRPV1GAAPOLBALDH1A1 | |
| SCHEMBL176305 | 0.72 | RXFP1 (0.54) | RXFP1TRPV1GAAPOLBMEN1 | |
| SCHEMBL28457710 | 0.72 | TRPV1 (0.53) | RXFP1TRPV1GAAPOLBALDH1A1 | |
| SCHEMBL3729968 | 0.72 | ALDH1A1 (0.45) | RXFP1TRPV1GAAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214326-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001018006-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |