Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CTRC | Q99895 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351223 | 0.92 | LMNA (0.33) | LMNAMAPTHTTBACE1ALOX5 | |
| SCHEMBL608536 | 0.84 | ALDH1A1 (0.50) | LMNAMAPTHTTBACE1ALOX5 | |
| SCHEMBL4611987 | 0.84 | ALDH1A1 (0.39) | LMNAMAPTHTTBACE1ALOX5 | |
| SCHEMBL29136487 | 0.82 | HDAC4 (0.47) | LMNAMAPTHTTBACE1ALOX5 | |
| Biphenyl SCHEMBL28876393 | 0.82 | ALDH1A1 (0.56) | LMNAMAPTHTTBACE1ALOX5 | |
| SCHEMBL14390391 | 0.82 | LMNA (0.48) | LMNAMAPTHTTBACE1ALOX5 | |
| SCHEMBL28710407 | 0.82 | LMNA (0.48) | LMNAMAPTHTTBACE1ALOX5 | |
| Water SCHEMBL28835132 | 0.82 | LMNA (0.48) | LMNAMAPTHTTBACE1ALOX5 | |
| SCHEMBL4612869 | 0.81 | ALDH1A1 (0.41) | LMNAMAPTHTTBACE1ALDH1A1 | |
| Water SCHEMBL28175107 | 0.79 | LMNA (0.46) | LMNAMAPTHTTBACE1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387545-B1 | TERTIARY AMINE SUBSTITUTED QUATERPHENYL COMPOUND FOR COMBINED HOLE-TRANSPORTING AND LIGHT-EMITTING LAYER OF BLUE COLOR ORGANIC ELECTROLUMINESCENT DEVICE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2002-05-14 | — | — | US | disclosed |