SCHEMBL4611987

SCHEMBL4611987

Ic1ccc(-c2ccccc2)c(-c2ccccc2)c1I

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
MAPK1 P28482 2/20 0.39
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.37
BACE1 P56817 1/20 0.36
ALOX5 P09917 1/20 0.35
HSD17B10 Q99714 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
CYP2A6 P11509 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
ESR2 Q92731 2/20 0.33
ESR1 P03372 1/20 0.33
TDO2 P48775 1/20 0.32
PARP1 P09874 1/20 0.32
CTRC Q99895 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19117105 0.86 LMNA (0.40) ALDH1A1MAPK1LMNAMAPTHTT
SCHEMBL7714896 0.84 LMNA (0.39) ALDH1A1MAPK1LMNAMAPTHTT
SCHEMBL11709715 0.81 TDO2 (0.39) ALDH1A1MAPK1BACE1ALOX5HSD17B10
SCHEMBL1768308 0.77 MAPK1 (0.39) ALDH1A1MAPK1LMNAMAPTHTT
SCHEMBL608536 0.77 ALDH1A1 (0.50) ALDH1A1MAPK1LMNAMAPTHTT
SCHEMBL4351223 0.77 LMNA (0.33) ALDH1A1MAPK1LMNAMAPTHTT
SCHEMBL29136487 0.76 HDAC4 (0.47) ALDH1A1LMNAMAPTHTTBACE1
Biphenyl SCHEMBL28876393 0.75 ALDH1A1 (0.56) ALDH1A1MAPK1LMNAMAPTHTT
SCHEMBL28710407 0.75 LMNA (0.48) ALDH1A1MAPK1LMNAMAPTHTT
SCHEMBL3360517 0.75 ALDH1A1 (0.47) ALDH1A1MAPK1BACE1ALOX5HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2535366-B1 POLYMER, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE MITSUBISHI CHEM CORP (JP) 2020-12-30 EP disclosed
US-10087289-B2 Monomers, oligomeric complexes, coordination polymers, and methods for their preparation and use EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2018-10-02 US disclosed
US-9349961-B2 Organic electroluminescent element material, organic electroluminescent element composition, organic electroluminescent element, display device, and lighting device MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-24 US disclosed
US-8653230-B2 Monomers, oligomeric complexes, coordination polymers, and methods for their preparation and use EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2014-02-18 US disclosed
US-20130200337-A1 ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT COMPOSITION, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-08-08 US disclosed
EP-2535366-A1 POLYMER, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, COMPOSITION FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE Mitsubishi Chemical Corporation (JP) 2012-12-19 EP disclosed
US-20120214962-A1 Monomers, Oligomeric Complexes, Coordination Polymers, and Methods for Their Preparation and Use EMPIRE TECHNOLOGY DEVELOPMENT LLC 2012-08-23 US disclosed
EP-1520846-B1 Method for producing polymerized hydrocarbon JFE CHEMICAL CORP (JP) 2008-03-05 EP disclosed
US-7138484-B2 Method for producing polymerized hydrocarbon JFE CHEMICAL CORPORATION (JP) 2006-11-21 US disclosed
US-20050075478-A1 Method for producing polymerized hydrocarbon JFE CHEMICAL CORPORATION (JP) 2005-04-07 US disclosed
EP-1520846-A1 Method for producing polymerized hydrocarbon JFE Chemical Corporation (JP) 2005-04-06 EP disclosed
US-6706850-B2 AROMATIC BLOCKS WITH BRANCHES OF ALIPHATIC POLYETHER CHAINS THAT HAVE LOWER THERMAL DECOMPOSITION TEMPERATURE FOR FORMATION OF POROUS ORGANIC FILMS THAT ALLOW LOWERING OF DIELECTRIC CONSTANT AS INSULATION MATERIALS IN ELECTRONICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-16 US disclosed
US-20020006999-A1 Polyether copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-17 US disclosed
US-4764625-A POTASSIUM HYDROXIDE, COPPER CATALYST XEROX CORPORATION (US) 1988-08-16 US disclosed
EP-0034425-B1 PROCESS FOR PREPARING ARYLAMINES XEROX CORPORATION (US) 1984-05-16 EP disclosed
EP-0034425-A2 Process for preparing arylamines XEROX CORPORATION (US) 1981-08-26 EP disclosed
EP-0029703-A1 Electrophotographic imaging member XEROX CORPORATION (US) 1981-06-03 EP disclosed