Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10788479 | 0.76 | GAA (0.48) | RAPGEF4GAAHPGDKMT2AMAPT | |
| SCHEMBL11804375 | 0.76 | LMNA (0.44) | ALDH1A1LMNACA2TDP1 | |
| SCHEMBL27745298 | 0.75 | CES1 (0.36) | SMN1; SMN2ALDH1A1HTTLMNA | |
| SCHEMBL13997435 | 0.74 | GAA (0.61) | RAPGEF4GAAHPGDKMT2AMAPT | |
| SCHEMBL14030962 | 0.72 | GAA (0.58) | RAPGEF4GAAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9001218 | 0.71 | RAPGEF4 (1.00) | RAPGEF4GAAHPGDKMT2AMAPT | |
| SCHEMBL4400955 | 0.71 | GAA (1.00) | RAPGEF4GAAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10067072 | 0.71 | GAA (1.00) | RAPGEF4GAAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL170033 | 0.71 | GAA (1.00) | RAPGEF4GAAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL811061 | 0.70 | ALDH1A1 (0.76) | RAPGEF4GAAHPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387395-B1 | N-[1, (1-1) -dialkyloxy] - and N- [1, (1-1) -dialkenyloxy]- alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor | EPPSTEIN DEBORAH A (US) | 2002-05-14 | — | — | US | disclosed |