Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 15/20 | 0.36 |
| ▸ | PLK4 | O00444 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.33 |
| ▸ | PRKX | P51817 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191595 | 0.97 | KDM4E (0.40) | KDM4EHPGDALDH1A1PARP1PLK4 | |
| Silver SCHEMBL4077437 | 0.97 | KDM4E (0.36) | KDM4EHPGDALDH1A1PARP1PLK4 | |
| Potassium Ion SCHEMBL6052365 | 0.97 | KDM4E (0.36) | KDM4EHPGDALDH1A1PARP1PLK4 | |
| Potassium Ion SCHEMBL11020659 | 0.95 | KDM4E (0.35) | KDM4EHPGDALDH1A1PARP1PLK4 | |
| SCHEMBL11019867 | 0.95 | KDM4E (0.39) | KDM4EHPGDALDH1A1PARP1PLK4 | |
| Silver SCHEMBL9638124 | 0.95 | KDM4E (0.35) | KDM4EHPGDALDH1A1PARP1PLK4 | |
| Silver SCHEMBL9637083 | 0.95 | KDM4E (0.35) | KDM4EHPGDALDH1A1PARP1PLK4 | |
| Tetraphenylphosphonium SCHEMBL6141578 | 0.87 | KDM4E (0.33) | KDM4EHPGDALDH1A1PARP1DHODH | |
| SCHEMBL2188295 | 0.84 | PARP1 (0.39) | KDM4EHPGDPARP1PLK4MAP4K4 | |
| SCHEMBL238610 | 0.82 | RIPK1 (0.35) | ALDH1A1PARP1AURKARPS6KB1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372027-B1 | ORGANOMETALLIC LAYER DEPOSITED ON INORGANIC SUBSTRATE BY TREATING WITH COMPOSITION COMPRISING A SILANE, AN AZOLE, AN OXYGEN CARRIER, AN ACID | ALFACHIMICI S.P.A. (IT) | 2002-04-16 | — | — | US | disclosed |
| EP-1114572-A1 | PROCESS FOR PROMOTING ADHESION BETWEEN AN INORGANIC SUBSTRATE AND AN ORGANIC POLYMER | ALFACHIMICI S.p.A. (IT) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000074451-A1 | PROCESS FOR PROMOTING ADHESION BETWEEN AN INORGANIC SUBSTRATE AND AN ORGANIC POLYMER | ALFACHIMICI S.P.A. (IT) | 2000-12-07 | — | — | WO | disclosed |