SCHEMBL238610

SCHEMBL238610

CCCC[P+](CCCC)(CCCC)CCCC.O=C([O-])c1cccc2[nH]nnc12

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.35
ALDH1A1 P00352 2/20 0.33
CA2 P00918 1/20 0.33
CYP3A4 P08684 1/20 0.33
RPS6KB1 P23443 1/20 0.33
PARP1 P09874 5/20 0.32
ALOX5 P09917 2/20 0.32
AURKA O14965 1/20 0.31
AURKB Q96GD4 1/20 0.31
LMNA P02545 1/20 0.31
LTB4R Q15722 2/20 0.30
TSHR P16473 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1228378 0.96 RIPK1 (0.33) RIPK1ALDH1A1CA2CYP3A4RPS6KB1
SCHEMBL6140866 0.96 DNM1 (0.35) RIPK1ALDH1A1CA2CYP3A4RPS6KB1
SCHEMBL6141204 0.95 RIPK1 (0.34) RIPK1ALDH1A1CYP3A4PARP1ALOX5
SCHEMBL30848497 0.94 PARP1 (0.35) RIPK1ALDH1A1CA2CYP3A4RPS6KB1
SCHEMBL4780253 0.91 PRSS1 (0.34) RIPK1ALDH1A1CA2CYP3A4PARP1
SCHEMBL6141401 0.90 RIPK1 (0.31) RIPK1RPS6KB1
SCHEMBL6141403 0.90 BDKRB2 (0.38) ALDH1A1CA2CYP3A4TSHR
Butyltriphenylphosphonium SCHEMBL6141574 0.87 ALDH1A1 (0.34) RIPK1ALDH1A1CA2CYP3A4RPS6KB1
SCHEMBL6141242 0.87 ALDH1A1 (0.33) RIPK1ALDH1A1CA2CYP3A4RPS6KB1
SCHEMBL6141547 0.87 PARP1 (0.35) RIPK1ALDH1A1RPS6KB1PARP1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220298293-A1 ALIPHATIC POLYISOCYANATE COMPOSITION, PREPARATION METHOD THEREFOR, AND COATING COMPOSITION WANHUA CHEMICAL GROUP CO., LTD. (CN) 2022-09-22 US claimed
EP-4056618-A1 ALIPHATIC POLYISOCYANATE COMPOSITION, PREPARARION METHOD THEREFOR, AND COATING COMPOSITION Wanhua Chemical Group Co., Ltd. (CN) 2022-09-14 EP claimed
CN-108148394-B Storage-stable one-component polyurethane prepregs from polyurethane compositions and moldings produced therefrom 赢创运营有限公司 2021-12-28 CN claimed
EP-3330311-B1 STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION EVONIK OPERATIONS GMBH (DE) 2021-05-05 EP claimed
US-10633519-B2 Storage-stable polyurethane prepregs and mouldings produced therefrom composed of a polyurethane composition with liquid resin components EVONIK OPERATIONS GMBH (DE) 2020-04-28 US claimed
US-10626236-B2 Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom EVONIK OPERATIONS GMBH (DE) 2020-04-21 US claimed
US-20180155515-A1 STORAGE-STABLE ONE-COMPONENT POLYURETHANE PREPREGS AND SHAPED BODIES COMPOSED OF POLYURETHANE COMPOSITION THAT HAVE BEEN PRODUCED THEREFROM EVONIK OPERATIONS GMBH (DE) 2018-06-07 US claimed
EP-3330311-A1 STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION Evonik Degussa GmbH (DE) 2018-06-06 EP claimed
EP-2411439-B1 PREPEGS AND MOLDED BODIES PRODUCED THEREOF AT LOW TEMPERATURE EVONIK DEGUSSA GMBH (DE) 2016-11-16 EP claimed
EP-2188320-B1 DUAL CURE FORMULATIONS WITH COMPONENTS COMPRISING URETDIONE GROUPS EVONIK DEGUSSA GMBH (DE) 2014-05-14 EP claimed
WO-2005085315-A1 POLYURETHANE COMPOSITIONS THAT CAN BE CURED AT LOW TEMPERATURES AND CONTAIN URETDIONE GROUPS DEGUSSA AG (DE) 2005-09-15 WO claimed
US-6926941-B2 Laminates of thermoplastic fluororesins and their manufacture ZEON CORPORATION (JP) 2005-08-09 US claimed
US-20040265528-A1 Line, in particular for fuel tank filler systems VERITAS AG (DE) 2004-12-30 US claimed
EP-1475406-A1 hose, particularly for fuel intake VERITAS AG (DE) 2004-11-10 EP claimed
US-20040038039-A1 Laminates of thermoplastic fluororesins and their manufacture ZEON CORPORATION (JP) 2004-02-26 US claimed
EP-1332178-A1 LAMINATES OF THERMOPLASTIC FLUORORESINS AND THEIR MANUFACTURE Zeon Corporation (JP) 2003-08-06 EP claimed
WO-2002038668-A1 LAMINATES OF THERMOPLASTIC FLUORORESINS AND THEIR MANUFACTURE ZEON CORPORATION (JP) 2002-05-16 WO claimed
EP-0759354-B1 LAMINATE OF VULCANIZABLE RUBBER COMPOSITION LAYERS, PROCESS FOR PRODUCING A VULCANIZED RUBBER LAMINATE, AND RUBBER LAMINATE NIPPON ZEON CO (JP) 2000-08-16 EP claimed
US-5855976-A HOSE, DIAPHRAGM NIPPON ZEON CO., LTD. (JP) 1999-01-05 US claimed
EP-0759354-A1 LAMINATE OF VULCANIZABLE RUBBER COMPOSITION LAYERS, PROCESS FOR PRODUCING RUBBER LAMINATE, AND RUBBER LAMINATE NIPPON ZEON CO., LTD. (JP) 1997-02-26 EP claimed