SCHEMBL7715573

SCHEMBL7715573

CCCCSC(=O)OCOC(=O)C(C)(C)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.41
ALDH1A1 P00352 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18655571 0.75 TDP1 (0.38) ACHEALDH1A1
SCHEMBL7869641 0.74 ALDH1A1 (0.33) ALDH1A1
SCHEMBL3114728 0.72 ALDH1A1 (0.50) ACHEALDH1A1
SCHEMBL28947501 0.71 NAAA (0.48) ACHEALDH1A1NPSR1
SCHEMBL6882142 0.71 ACHE (0.40) ACHEALDH1A1
SCHEMBL6577987 0.70 ACHE (0.61) ACHEALDH1A1NOS3NOS1NOS2
SCHEMBL10515804 0.69 NAAA (0.52) ACHEALDH1A1NPSR1
SCHEMBL9153319 0.69 NAAA (0.52) ACHEALDH1A1NPSR1
SCHEMBL14566016 0.69 NAAA (0.52) ACHEALDH1A1NPSR1
SCHEMBL7067758 0.69 ACHE (0.50) ACHEALDH1A1NPSR1NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376548-B1 FUNGICIDES; HERBICIDES; INSECTICIDES ROHM AND HAAS COMPANY 2002-04-23 US disclosed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed