SCHEMBL7715841

SCHEMBL7715841

O=COCC(=S)Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.43
CES2 O00748 1/20 0.43
AKR1B1 P15121 1/20 0.43
PAM P19021 1/20 0.43
ALDH1A1 P00352 1/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
TSHR P16473 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
FNTA P49354 1/20 0.37
FNTB P49356 1/20 0.37
MAOB P27338 1/20 0.37
GAA P10253 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270514 0.81 CES1 (0.48) CES1CES2AKR1B1PAMALDH1A1
SCHEMBL7715836 0.76 CES1 (0.42) CES1CES2AKR1B1PAMALDH1A1
SCHEMBL10402623 0.74 CES1 (0.45) CES1CES2AKR1B1PAMALDH1A1
SCHEMBL10402622 0.74 CES1 (0.45) CES1CES2AKR1B1PAMALDH1A1
SCHEMBL10767367 0.74 TDP1 (0.39) CES1CES2ALDH1A1MAPK1L3MBTL1
SCHEMBL3826465 0.74 LMNA (0.50) CES1CES2AKR1B1PAMALDH1A1
Hydroxyamine SCHEMBL27588656 0.74 ALDH1A1 (0.48) CES1CES2AKR1B1ALDH1A1MAPK1
SCHEMBL28317560 0.73 CA1 (0.44) ALDH1A1MAPK1L3MBTL1MEN1KMT2A
Phenylacetic Acid SCHEMBL30136468 0.72 AKR1B1 (0.63) CES1CES2AKR1B1PAMALDH1A1
SCHEMBL8847908 0.72 ALDH1A1 (0.61) CES1CES2AKR1B1PAMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6365552-B1 AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 2002-04-02 US disclosed
US-5928999-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-07-27 US disclosed