Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | MET | P08581 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516946 | 0.85 | ALDH1A1 (0.77) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL7715224 | 0.84 | PTPN1 (0.71) | ALDH1A1TSHRCYP3A4TDP1PTPN1 | |
| SCHEMBL11675822 | 0.81 | PTPN1 (0.54) | ALDH1A1TSHRCYP3A4HSD17B10CYP19A1 | |
| SCHEMBL27422297 | 0.78 | PTPN1 (0.77) | ALDH1A1TSHRCYP3A4TDP1PTPN1 | |
| SCHEMBL31337400 | 0.78 | PTPN1 (0.77) | ALDH1A1TSHRCYP3A4TDP1PTPN1 | |
| SCHEMBL8868058 | 0.78 | ALDH1A1 (0.67) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL5132141 | 0.78 | ALDH1A1 (0.71) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL1299605 | 0.76 | ALDH1A1 (0.69) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL13181141 | 0.76 | ALDH1A1 (0.69) | ALDH1A1TSHRCYP3A4HSD17B10TDP1 | |
| SCHEMBL28403764 | 0.76 | AKR1B1 (0.69) | CYP19A1METPTPN1AKR1B1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376524-B1 | ANTIALLERGENS, ANTIHISTAMINES | SUNESIS PHARMACEUTICALS, INC. | 2002-04-23 | — | — | US | disclosed |
| WO-2001098245-A2 | TRIPHENYL COMPOUNDS AS INTERLEUKIN-4 ANTAGONISTS | SUNESIS PHARMACEUTICALS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |