Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282581 | 0.89 | LMNA (0.64) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL13258018 | 0.84 | GSTP1 (0.58) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL1437775 | 0.84 | APP (0.64) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL10497967 | 0.83 | KCNA3 (0.53) | HDAC6L3MBTL1LTA4HFFAR1TRPA1 | |
| SCHEMBL8885157 | 0.83 | LTA4H (0.50) | CYP1A2CYP2C19MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL25297779 | 0.83 | LMNA (0.53) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL2068920 | 0.83 | MAOB (0.57) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| Benzyl Bromide SCHEMBL1043932 | 0.82 | TSHR (0.70) | MAOBGAASMN1; SMN2TRPA1ALDH1A1 | |
| SCHEMBL1044357 | 0.81 | LTA4H (0.53) | CYP1A2CYP2C19L3MBTL1LTA4HCA12 | |
| SCHEMBL30705746 | 0.80 | TRPA1 (0.59) | MAOBGAAMAOATRPA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376524-B1 | ANTIALLERGENS, ANTIHISTAMINES | SUNESIS PHARMACEUTICALS, INC. | 2002-04-23 | — | — | US | disclosed |
| WO-2001098245-A2 | TRIPHENYL COMPOUNDS AS INTERLEUKIN-4 ANTAGONISTS | SUNESIS PHARMACEUTICALS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |