Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 7/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715892 | 0.86 | KCNQ2 (0.50) | KCNQ2SIGMAR1LMNA | |
| SCHEMBL7715909 | 0.85 | KCNQ2 (0.48) | KCNQ2SIGMAR1LMNAMEN1KMT2A | |
| SCHEMBL7716793 | 0.70 | MAPK8 (0.51) | KCNQ2SIGMAR1ALDH1A1 | |
| SCHEMBL8008257 | 0.69 | SIGMAR1 (0.52) | KCNQ2SIGMAR1 | |
| SCHEMBL8008253 | 0.69 | SIGMAR1 (0.52) | KCNQ2SIGMAR1 | |
| SCHEMBL8005302 | 0.68 | KCNQ2 (0.47) | KCNQ2SIGMAR1 | |
| SCHEMBL8006026 | 0.68 | SIGMAR1 (0.51) | KCNQ2SIGMAR1ALDH1A1 | |
| SCHEMBL7833553 | 0.68 | SIGMAR1 (0.40) | KCNQ2SIGMAR1LMNAMEN1KMT2A | |
| SCHEMBL8005511 | 0.67 | SIGMAR1 (0.50) | KCNQ2SIGMAR1LMNAMEN1KMT2A | |
| SCHEMBL8005502 | 0.67 | SIGMAR1 (0.50) | KCNQ2SIGMAR1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |