Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715893 | 0.85 | KCNQ2 (0.54) | KCNQ2SIGMAR1MEN1KMT2ALMNA | |
| SCHEMBL7715892 | 0.83 | KCNQ2 (0.50) | KCNQ2SIGMAR1ADRA1DADRA1AADRA1B | |
| SCHEMBL8005511 | 0.83 | SIGMAR1 (0.50) | KCNQ2SIGMAR1MAPTL3MBTL1MEN1 | |
| SCHEMBL8005502 | 0.83 | SIGMAR1 (0.50) | KCNQ2SIGMAR1MAPTL3MBTL1MEN1 | |
| SCHEMBL7718916 | 0.76 | NPY1R (0.50) | NPY1RMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7718950 | 0.76 | NPY1R (0.50) | NPY1RMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7711275 | 0.75 | NPY1R (0.54) | NPY1RMAPTKMT2ALMNAMAPK1 | |
| SCHEMBL7718948 | 0.72 | NPY1R (0.49) | NPY1RMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7711176 | 0.71 | ADRA1A (0.66) | NPY1RADRA1DADRA1AADRA1B | |
| SCHEMBL7715978 | 0.71 | ADRA1A (0.66) | NPY1RADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376503-B1 | TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC | 2002-04-23 | — | — | US | disclosed |