Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720171 | 0.96 | ATM (0.49) | ATMLMNATLR8TLR7CYP3A4 | |
| SCHEMBL27850567 | 0.82 | ATM (0.44) | ATMLMNATLR8CYP3A4TRPV1 | |
| SCHEMBL16178787 | 0.79 | ATM (0.50) | ATMLMNATLR8CYP3A4TRPV1 | |
| SCHEMBL9001640 | 0.79 | CCR1 (0.46) | ATMLMNATLR8CYP3A4TRPV1 | |
| SCHEMBL27851167 | 0.79 | LMNA (0.53) | LMNATLR8TLR7CYP3A4TRPV1 | |
| SCHEMBL27958879 | 0.76 | TLR7 (0.37) | TLR8TLR7CYP3A4TRPV1KDM4E | |
| SCHEMBL17099988 | 0.75 | LMNA (0.51) | ATMLMNACYP3A4KDM4EMAPT | |
| Phosphoric Acid SCHEMBL29226180 | 0.74 | ATM (0.48) | ATMLMNACYP3A4KDM4EMAPT | |
| SCHEMBL4242510 | 0.74 | TLR8 (0.50) | TLR8TLR7TRPV1KDM4EMAPT | |
| SCHEMBL8944496 | 0.74 | LMNA (0.50) | ATMLMNACYP3A4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391648-B1 | ASSOCIATIONS FOR USE AS OPTICAL OXYGEN DETECTORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-05-21 | — | — | US | disclosed |
| EP-1159373-A2 | PHOTOLUMINESCENT METAL-(BIS)LIGAND COMPLEXES HAVING DIFFERENT LIGANDS | The Regents of the University of California (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000050534-A2 | PHOTOLUMINESCENT METAL-(BIS)LIGAND COMPLEXES HAVING DIFFERENT LIGANDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-31 | — | — | WO | disclosed |