SCHEMBL7720171

SCHEMBL7720171

CCCCc1cc2ccc3ncccc3c2nc1CCCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.49
LMNA P02545 1/20 0.45
CYP3A4 P08684 2/20 0.40
TLR8 Q9NR97 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 1/20 0.39
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36
IDO1 P14902 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
GABRA4 P48169 1/20 0.36
GABRE P78334 1/20 0.36
GABRA6 Q16445 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7715992 0.96 ATM (0.48) ATMLMNACYP3A4TLR8KDM4E
SCHEMBL9001640 0.82 CCR1 (0.46) ATMLMNACYP3A4TLR8KDM4E
SCHEMBL16678778 0.78 LMNA (0.54) LMNACYP3A4TLR8KDM4EMAPT
SCHEMBL27850567 0.77 ATM (0.44) ATMLMNACYP3A4TLR8KDM4E
SCHEMBL17099988 0.76 LMNA (0.51) ATMLMNACYP3A4KDM4EMAPT
Phosphoric Acid SCHEMBL29226180 0.75 ATM (0.48) ATMLMNACYP3A4KDM4EMAPT
SCHEMBL1586524 0.75 LMNA (0.50) ATMLMNACYP3A4KDM4EMAPT
SCHEMBL8944496 0.75 LMNA (0.50) ATMLMNACYP3A4KDM4EMAPT
SCHEMBL28732762 0.75 LMNA (0.50) LMNACYP3A4KDM4EMAPTTRPV1
SCHEMBL16178787 0.75 ATM (0.50) ATMLMNACYP3A4TLR8KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0628805-B1 Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution AVL MEDICAL INSTR AG (CH) 1996-09-18 EP claimed
US-5464587-A In blood AVL MEDICAL INSTRUMENTS AG (CH) 1995-11-07 US claimed
EP-0628805-A1 Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution AVL Medical Instruments AG (CH) 1994-12-14 EP claimed
US-6391648-B1 ASSOCIATIONS FOR USE AS OPTICAL OXYGEN DETECTORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-05-21 US disclosed
EP-1159373-A2 PHOTOLUMINESCENT METAL-(BIS)LIGAND COMPLEXES HAVING DIFFERENT LIGANDS The Regents of the University of California (US) 2001-12-05 EP disclosed
WO-2000050534-A2 PHOTOLUMINESCENT METAL-(BIS)LIGAND COMPLEXES HAVING DIFFERENT LIGANDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2000-08-31 WO disclosed
EP-0628805-B1 Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution AVL MEDICAL INSTR AG (CH) 1996-09-18 EP disclosed
US-5464587-A In blood AVL MEDICAL INSTRUMENTS AG (CH) 1995-11-07 US disclosed
EP-0628805-A1 Luminescent optical indicator for measuring the activity of alkali metal ions in a sample solution AVL Medical Instruments AG (CH) 1994-12-14 EP disclosed