Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491890 | 0.85 | LMNA (0.59) | KMT2AMEN1ALDH1A1KDM4EP2RX1 | |
| SCHEMBL7716098 | 0.80 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL492434 | 0.78 | KMT2A (0.74) | KMT2AMEN1ALDH1A1MAPTLMNA | |
| SCHEMBL27564373 | 0.76 | KMT2A (0.47) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL6591721 | 0.76 | P2RX1 (0.64) | KMT2AMEN1ALDH1A1MAPTP2RX1 | |
| SCHEMBL491122 | 0.75 | KMT2A (0.57) | KMT2AMEN1ALDH1A1MAPTP2RX1 | |
| SCHEMBL491924 | 0.73 | KMT2A (0.63) | KMT2AMEN1ALDH1A1MAPTP2RX1 | |
| SCHEMBL491965 | 0.72 | LMNA (0.62) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL6594872 | 0.72 | P2RX1 (0.58) | KMT2AMEN1ALDH1A1MAPTP2RX1 | |
| SCHEMBL27782904 | 0.71 | KDM1A (0.64) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6335334-B1 | HYPERTENSIVE AGENTS, ANTICOAGULANTS; CARDIOVASCULAR AND SEXUAL DISORDERS, ANGINA PECTORIS, AND ATHEROSCLEROSIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-01-01 | — | — | US | disclosed |