Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | FGB | P02675 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532073 | 0.88 | SRD5A1 (0.51) | PTPRCSRD5A1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL883773 | 0.88 | SRD5A1 (0.51) | PTPRCSRD5A1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL353895 | 0.85 | BAZ2B (0.56) | PTPRCSRD5A1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13727452 | 0.82 | BAZ2B (0.52) | PTPRCSRD5A1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL5204433 | 0.82 | SRD5A2 (0.55) | PTPRCSRD5A1SRD5A2ALDH1A1HSP90AA1 | |
| SCHEMBL13548832 | 0.81 | MAPK14 (0.56) | PTPRCSRD5A1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL484748 | 0.76 | PBRM1 (0.51) | PTPRCSRD5A1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16499680 | 0.75 | PTPRC (0.46) | PTPRCSRD5A1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL26187743 | 0.75 | ALDH1A1 (0.44) | PTPRCSRD5A1SRD5A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8142034 | 0.74 | SRD5A1 (0.56) | PTPRCSRD5A1SRD5A2ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339082-B1 | FOR THERAPY OF DISEASES CAUSED BY LOSS OF BONE MATRIX | AVENTIS PHARMA S.A. (FR) | 2002-01-15 | — | — | US | disclosed |