Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2258053 | 0.90 | ALDH1A1 (0.50) | MAPK14ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL29446230 | 0.90 | SMN1; SMN2 (0.50) | MAPK14ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL354166 | 0.90 | SMN1; SMN2 (0.50) | MAPK14ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL31532073 | 0.87 | SRD5A1 (0.51) | MAPK14ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL883773 | 0.87 | SRD5A1 (0.51) | MAPK14ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL31337617 | 0.83 | BRD4 (0.55) | PBRM1MAPK14ALDH1A1SMN1; SMN2SRD5A1 | |
| SCHEMBL30583381 | 0.83 | BRD4 (0.55) | PBRM1MAPK14ALDH1A1SMN1; SMN2SRD5A1 | |
| SCHEMBL10502958 | 0.82 | ALOX15 (0.45) | PBRM1MAPK14ALDH1A1ATMSMN1; SMN2 | |
| SCHEMBL9372469 | 0.81 | MAPK14 (0.57) | MAPK14ALDH1A1SMN1; SMN2SRD5A1SRD5A2 | |
| SCHEMBL12365119 | 0.81 | MAPK14 (0.50) | MAPK14ALDH1A1ATMSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112274046-B | Antibacterial towel rack and preparation process thereof | 温州欧迪家居用品有限公司 | 2022-07-22 | — | — | CN | claimed |
| CN-112274046-A | Antibacterial towel rack and preparation process thereof | 温州欧迪家居用品有限公司 | 2021-01-29 | — | — | CN | claimed |
| CN-114907389-A | Boronic acid derivatives | 首药控股(北京)股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-112274046-B | Antibacterial towel rack and preparation process thereof | 温州欧迪家居用品有限公司 | 2022-07-22 | — | — | CN | disclosed |
| US-20220135539-A1 | BIARYL AMIDE COMPOUNDS, PREPARATION METHODS AND MEDICAL APPLICATIONS THEREOF | Eternity Bioscience Inc. | 2022-05-05 | — | — | US | disclosed |
| EP-2962992-B1 | FULLERENE DERIVATIVE, ORGANIC SOLAR CELL USING SAME, AND MANUFACTURING METHOD THEREOF | LG CHEMICAL LTD (KR) | 2021-07-07 | — | — | EP | disclosed |
| CN-112274046-A | Antibacterial towel rack and preparation process thereof | 温州欧迪家居用品有限公司 | 2021-01-29 | — | — | CN | disclosed |
| EP-2704571-B1 | AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS | MERCK SHARP & DOHME (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-2704571-B1 | AMINO-PYRIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS | MERCK SHARP & DOHME (US) | 2020-04-22 | — | — | EP | disclosed |
| US-9522882-B2 | Strigolactam derivatives as plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-20 | — | — | US | disclosed |
| US-9522882-B2 | Strigolactam derivatives as plant growth regulating compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-20 | — | — | US | disclosed |
| US-20100249095-A1 | Substituted Spiro-amide Compounds | GRUENENTHAL GMBH (DE) | 2010-09-30 | — | — | US | disclosed |
| US-20100249095-A1 | Substituted Spiro-amide Compounds | GRUENENTHAL GMBH (DE) | 2010-09-30 | — | — | US | disclosed |
| US-20100249095-A1 | Substituted Spiro-amide Compounds | GRUENENTHAL GMBH (DE) | 2010-09-30 | — | — | US | disclosed |
| WO-2010108651-A1 | SUBSTITUTED SPIRO-AMIDE COMPOUNDS | Grünenthal GmbH (DE) | 2010-09-30 | — | — | WO | disclosed |
| EP-0657426-B1 | Tricyclic pyrrole derivatives | HOFFMANN LA ROCHE (CH) | 1998-07-22 | — | — | EP | disclosed |
| US-5646173-A | ANTISEROTONINE AGENTS; CENTRAL NERVOUS SYSTEM DISORDERS; ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1997-07-08 | — | — | US | disclosed |
| US-5525617-A | ANTICOAGULANT | MERCK & CO., INC. (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1996015099-A1 | HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1996-05-23 | — | — | WO | disclosed |
| EP-0657426-A2 | Tricyclic pyrrole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1995-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135539-A1 | BIARYL AMIDE COMPOUNDS, PREPARATION METHODS AND MEDICAL APPLICATIONS THEREOF | BRAF, NRAS, RAF1 | PBRM1 386/4885MAPK14 1089/4885ALDH1A1 1618/4885 |
| US-20100249095-A1 | Substituted Spiro-amide Compounds | BDKRB1, BDKRB2, REN | PBRM1 916/4885MAPK14 2645/4885ALDH1A1 2086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.