Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 2/20 | 0.31 |
| ▸ | KLK1 | P06870 | 2/20 | 0.31 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715530 | 0.83 | ACP1 (0.32) | TP53ATMHDAC1HDAC6ACP1 | |
| SCHEMBL7716181 | 0.80 | TP53 (0.36) | TP53MAPTP2RX3SLC2A1MEN1 | |
| SCHEMBL7716176 | 0.80 | AKR1C3 (0.36) | TP53MAPTATMHDAC1SLC2A1 | |
| SCHEMBL7716171 | 0.80 | TP53 (0.36) | TP53MAPTP2RX3SLC2A1MEN1 | |
| SCHEMBL7105529 | 0.78 | KMT2A (0.34) | TP53MAPTP2RX3HDAC1HDAC6 | |
| SCHEMBL7714244 | 0.77 | ACP1 (0.36) | TP53MAPTP2RX3ACP1MEN1 | |
| SCHEMBL7714237 | 0.77 | ACP1 (0.36) | TP53MAPTP2RX3ACP1MEN1 | |
| SCHEMBL7105250 | 0.75 | EGFR (0.40) | TP53MAPTKMT2A | |
| SCHEMBL7714210 | 0.71 | ITGB1 (0.42) | — | |
| SCHEMBL7714207 | 0.71 | ITGB1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403608-B1 | ANTIINFLAMMATORY AND IMMUNE DISORDERS | CELLTECH R&D, LTD. (GB) | 2002-06-11 | — | — | US | disclosed |