Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL8300809 | 1.00 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL2074977 | 0.92 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL2074979 | 0.92 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL14290264 | 0.83 | — | — | |
| SCHEMBL3295691 | 0.81 | — | — | |
| Ethylene SCHEMBL11442949 | 0.78 | SHBG (0.31) | — | |
| SCHEMBL8349202 | 0.77 | — | — | |
| SCHEMBL1003675 | 0.77 | — | — | |
| SCHEMBL7648990 | 0.77 | — | — | |
| SCHEMBL4515462 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372762-B1 | HETEROCYCLIC COMPOUNDS FOR NERVOUS SYSTEM DISORDERS | PFIZER INC. | 2002-04-16 | — | — | US | disclosed |
| EP-0953567-A2 | Bicyclic substituted piperazine-, piperidine- and tetrahydropyridine derivatives, their preparation and their use as agents with central dopaminergic (dopamine D4 receptor) activity | Pfizer Products Inc. (US) | 1999-11-03 | — | — | EP | disclosed |