SCHEMBL2074979

SCHEMBL2074979

O=C1CC2CC(=O)CC2C1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
MAP3K14 Q99558 1/20 0.32
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2074977 1.00 MAPK1 (0.35) MAPK1MAP3K14TRIM24TRIM33SMN1; SMN2
Ethylene SCHEMBL8300809 0.92 MAPK1 (0.32) MAPK1
Ethylene SCHEMBL7716211 0.92 MAPK1 (0.32) MAPK1
SCHEMBL3295691 0.89
SCHEMBL7648990 0.84
SCHEMBL8349202 0.84
SCHEMBL4515462 0.84
SCHEMBL1003675 0.84
SCHEMBL12777784 0.84
SCHEMBL14290264 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
WO-2022159439-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2022-07-28 WO claimed
US-7566710-B2 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof Centre National de la Racherche Scientifique (C.N.R.S.) (FR) 2009-07-28 US claimed
EP-1268470-B1 DUAL MOLECULES CONTAINING A PEROXIDE DERIVATIVE, SYNTHESIS AND THERAPEUTIC APPLICATIONS THEREOF CENTRE NAT RECH SCIENT (FR) 2008-02-27 EP claimed
US-20050288315-A1 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2005-12-29 US claimed
US-6949569-B2 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2005-09-27 US claimed
US-6287829-B1 USING CHIRAL ANCHOR-PROTECTIVE GROUPS DSM FINE CHEMICAL AUSTRIA NFG GMBH & CO KG (AT) 2001-09-11 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
US-4921923-A Ethers of oligomeric phenol-diketone condensation products and a vinyl-benzyl compound ALLIED SIGNAL INC. (US) 1990-05-01 US claimed
EP-0033863-A1 Process for the production of cis-bicyclo (3.3.0)octane-3,7-dione, and its use MERCK PATENT GmbH (DE) 1981-08-19 EP claimed
JP-7118207-A None JP disclosed
US-20250263398-A1 PROCESS ASSEMBLY BIOSCIENCES, INC. (US) 2025-08-21 US disclosed
CN-116648248-B Aromatic compound, pharmaceutical composition containing same and application thereof 成都茵创园医药科技有限公司 2025-04-15 CN disclosed
WO-2024255765-A1 NOVEL COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND USES THEREOF NUPHASE THERAPEUTICS (HANGZHOU) LIMITED., CO. (CN) 2024-12-19 WO disclosed
US-20240360114-A1 FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2024-10-31 US disclosed
WO-1988003568-A1 STEREOSPECIFIC KETO-REDUCTION OF BICYCLOOCTANDIONE-CARBOXYLIC ACID ESTERS BY MICROORGANISMS SCHERING AKTIENGESELLSCHAFT (DE) 1988-05-19 WO disclosed
WO-1988003526-A1 NEW PROCESS FOR MANUFACTURING OPTICALLY ACTIVE CARBOCYCLINE INTERMEDIATES SCHERING AKTIENGESELLSCHAFT (DE) 1988-05-19 WO disclosed
US-4307112-A 9-Deoxy-9A-methylene isosteres of PGI2 and process for their preparation FARMITALIA CARLO ERBA S.P.A. (IT) 1981-12-22 US disclosed
EP-0033863-A1 Process for the production of cis-bicyclo (3.3.0)octane-3,7-dione, and its use MERCK PATENT GmbH (DE) 1981-08-19 EP disclosed
US-4277600-A Tetraphenolic compounds and polycarbonates containing the same GENERAL ELECTRIC COMPANY (US) 1981-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360114-A1 FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF AIFM2, GPX1, GPX4 MAPK1 2778/4885MAP3K14 2857/4885TRIM24 4457/4885
US-20250263398-A1 PROCESS HCCS, HMBS, HAVCR2 MAPK1 2800/4885MAP3K14 2197/4885TRIM24 2399/4885
US-20050288315-A1 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof DUOX2, DUOX1, QSOX1 MAPK1 1199/4885MAP3K14 3894/4885TRIM24 4742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.