SCHEMBL2074977

SCHEMBL2074977

O=C1C[C@H]2CC(=O)C[C@H]2C1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.35
MAP3K14 Q99558 1/20 0.32
TRIM24 O15164 1/20 0.31
TRIM33 Q9UPN9 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2074979 1.00 MAPK1 (0.35) MAPK1MAP3K14TRIM24TRIM33SMN1; SMN2
Ethylene SCHEMBL8300809 0.92 MAPK1 (0.32) MAPK1
Ethylene SCHEMBL7716211 0.92 MAPK1 (0.32) MAPK1
SCHEMBL3295691 0.89
SCHEMBL7648990 0.84
SCHEMBL8349202 0.84
SCHEMBL4515462 0.84
SCHEMBL1003675 0.84
SCHEMBL12777784 0.84
SCHEMBL14290264 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-7566710-B2 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof Centre National de la Racherche Scientifique (C.N.R.S.) (FR) 2009-07-28 US claimed
EP-1268470-B1 DUAL MOLECULES CONTAINING A PEROXIDE DERIVATIVE, SYNTHESIS AND THERAPEUTIC APPLICATIONS THEREOF CENTRE NAT RECH SCIENT (FR) 2008-02-27 EP claimed
US-20050288315-A1 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2005-12-29 US claimed
US-6949569-B2 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2005-09-27 US claimed
US-20040038957-A1 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2004-02-26 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
EP-0033863-A1 Process for the production of cis-bicyclo (3.3.0)octane-3,7-dione, and its use MERCK PATENT GmbH (DE) 1981-08-19 EP claimed
EP-4653428-A1 PHARMACEUTICALLY ACCEPTABLE SALT AND CRYSTAL FORM OF TRIAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2025-11-26 EP disclosed
US-20240317725-A1 LPA1 SMALL MOLECULE ANTAGONIST TUOJIE BIOTECH (SHANGHAI) CO., LTD. (CN) 2024-09-26 US disclosed
WO-2024153219-A1 PHARMACEUTICALLY ACCEPTABLE SALT AND CRYSTAL FORM OF TRIAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR 江苏恒瑞医药股份有限公司 2024-07-25 WO disclosed
CN-118359590-A Triazole compound 上海拓界生物医药科技有限公司 2024-07-19 CN disclosed
EP-0270481-A1 Process for the preparation of optically active carbacyclin intermediates SCHERING AKTIENGESELLSCHAFT (DE) 1988-06-08 EP disclosed
WO-1988003568-A1 STEREOSPECIFIC KETO-REDUCTION OF BICYCLOOCTANDIONE-CARBOXYLIC ACID ESTERS BY MICROORGANISMS SCHERING AKTIENGESELLSCHAFT (DE) 1988-05-19 WO disclosed
WO-1988003526-A1 NEW PROCESS FOR MANUFACTURING OPTICALLY ACTIVE CARBOCYCLINE INTERMEDIATES SCHERING AKTIENGESELLSCHAFT (DE) 1988-05-19 WO disclosed
EP-0033863-A1 Process for the production of cis-bicyclo (3.3.0)octane-3,7-dione, and its use MERCK PATENT GmbH (DE) 1981-08-19 EP disclosed
EP-0033863-A1 Process for the production of cis-bicyclo (3.3.0)octane-3,7-dione, and its use MERCK PATENT GmbH (DE) 1981-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040038957-A1 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof DUOX1, DUOX2, CYC1 MAPK1 955/4885MAP3K14 3533/4885TRIM24 4499/4885
US-20050288315-A1 Dual molecules containing a peroxide derivative, synthesis and therapeutic applications thereof DUOX2, DUOX1, QSOX1 MAPK1 1199/4885MAP3K14 3894/4885TRIM24 4742/4885
US-20240317725-A1 LPA1 SMALL MOLECULE ANTAGONIST LPAR1, LPAR2, LPAR4 MAPK1 197/4885MAP3K14 930/4885TRIM24 3446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.