SCHEMBL7716407

SCHEMBL7716407

COc1cc(N)c(S(=O)(=O)O)cc1N=Nc1ccc(S(=O)(=O)CCOS(=O)(=O)O)c(S(=O)(=O)CCOS(=O)(=O)O)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
THRB P10828 3/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
RECQL P46063 2/20 0.38
BLM P54132 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX15 P16050 1/20 0.38
APEX1 P27695 1/20 0.38
MAPK1 P28482 1/20 0.38
BRCA1 P38398 1/20 0.38
SLC10A1 Q14973 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ENPP2 Q13822 2/20 0.38
PHLPP2 Q6ZVD8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7712999 0.89 THRB (0.44) MEN1KMT2ATHRBALDH1A1MAPT
SCHEMBL7717688 0.86 MEN1 (0.44) MEN1KMT2ATHRBALDH1A1MAPT
SCHEMBL17384275 0.84 PHLPP2 (0.44) MEN1KMT2ATHRBALDH1A1MAPT
SCHEMBL8811065 0.84 PTGS1 (0.40) MEN1KMT2ATHRBALDH1A1MAPT
SCHEMBL9750433 0.82 TP53 (0.34) MEN1KMT2ATHRBALDH1A1MAPT
SCHEMBL9881187 0.78 HSD17B10 (0.47) MEN1KMT2ATHRBALDH1A1MAPT
SCHEMBL4338500 0.78 PHLPP2 (0.54) MEN1KMT2ATHRBALDH1A1MAPT
SCHEMBL4338493 0.78 PHLPP2 (0.54) MEN1KMT2ATHRBALDH1A1MAPT
SCHEMBL7720103 0.78 SENP2 (0.47) MEN1KMT2ATHRBALDH1A1MAPT
SCHEMBL13743964 0.77 BRD4 (0.44) MEN1KMT2ATHRBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376656-B1 DISAZO DYES, TRIAZINE DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-04-23 US disclosed
US-6025478-A HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS BAYER AG (DE) 2000-02-15 US disclosed
US-5686642-A Compounds useful for the preparation of bi-and polyfunctional reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1997-11-11 US disclosed
US-5597902-A MONOAZO DYES, DISAZO DYES, NAPHTHOL DYES AND TRIAZO DYES FOR SILK, WOOL, LEATHER AND POLYAMIDES OR CELLULOSE BAYER AKTIENGESELLSCHAFT (DE) 1997-01-28 US disclosed
US-5502174-A Reactive dyestuffs based on a substituted barbituric acid BAYER AKTIENGESELLSCHAFT (DE) 1996-03-26 US disclosed
US-5093484-A Water soluble; colorfast shades on cotton BAYER AKTIENGESELLSCHAFT (DE) 1992-03-03 US disclosed