Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 7/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.37 |
| ▸ | SUMO2 | P61956 | 5/20 | 0.37 |
| ▸ | SUMO1 | P63165 | 5/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.37 |
| ▸ | SENP3 | Q9H4L4 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7716407 | 0.84 | MEN1 (0.38) | PTGS1PTGS2SENP2SENP1SUMO2 | |
| SCHEMBL9750422 | 0.84 | SENP2 (0.38) | PTGS1PTGS2SENP2SENP1SUMO2 | |
| SCHEMBL9749721 | 0.83 | THRB (0.47) | PTGS1PTGS2SENP2SENP1SUMO2 | |
| SCHEMBL7720103 | 0.82 | SENP2 (0.47) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL8819477 | 0.81 | SMN1; SMN2 (0.37) | PTGS1PTGS2KDM4EALDH1A1MAPT | |
| SCHEMBL7718129 | 0.81 | SENP2 (0.46) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL9750092 | 0.79 | SENP2 (0.40) | SENP2SENP1SUMO2SUMO1SENP7 | |
| SCHEMBL6938609 | 0.79 | HSD17B10 (0.39) | KDM4EALDH1A1MAPTMAPK1HSD17B10 | |
| SCHEMBL7712999 | 0.78 | THRB (0.44) | PTGS1PTGS2SENP2SENP1SUMO2 | |
| SCHEMBL7717688 | 0.76 | MEN1 (0.44) | PTGS1SENP2SENP1SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686642-A | Compounds useful for the preparation of bi-and polyfunctional reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-11 | — | — | US | disclosed |
| US-5597902-A | MONOAZO DYES, DISAZO DYES, NAPHTHOL DYES AND TRIAZO DYES FOR SILK, WOOL, LEATHER AND POLYAMIDES OR CELLULOSE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-28 | — | — | US | disclosed |
| US-5502174-A | Reactive dyestuffs based on a substituted barbituric acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5093484-A | Water soluble; colorfast shades on cotton | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |