Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.37 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.35 |
| ▸ | F2R | P25116 | 6/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719751 | 0.90 | LMNA (0.44) | PLGPLATLMNAKDM5AKDM4C | |
| SCHEMBL7719764 | 0.88 | PLG (0.46) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL6877330 | 0.80 | KDM5A (0.47) | LMNAKDM5AKDM4CPHF8KDM2A | |
| SCHEMBL12926818 | 0.79 | LMNA (0.56) | PLGPLATLMNAKDM5AKDM4C | |
| Hydrochloric Acid SCHEMBL1677750 | 0.79 | KDM5A (0.46) | LMNAKDM5AKDM4CPHF8KDM2A | |
| SCHEMBL8388643 | 0.75 | KDM5A (0.41) | LMNAKDM5AKDM4CPHF8KDM2A | |
| SCHEMBL7723458 | 0.75 | PLG (0.47) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL11664391 | 0.74 | LMNA (0.65) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL5165942 | 0.74 | LMNA (0.50) | PLGPLATLMNAANPEPENPEP | |
| SCHEMBL27534337 | 0.74 | LMNA (0.50) | PLGPLATLMNAANPEPENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417396-B1 | BY-PRODUCT INHIBITION; REACTING ORGANIC ALKALI OR ALKALINE EARTH METAL CARBOXYLATE, PHOSPHONATE, OR SULFONATE; ACYLATION, PHOSPHORYLATION, SULFONATION, AMIDATION, ALKYLATION, CYCLIZATION, OR CONDENSATION | Lambert, Warner | 2002-07-09 | — | — | US | disclosed |
| US-6395930-B1 | AMINE SULFIDE PHOSPHATE OR SULFATE REAGENTS | WARNER LAMBERT | 2002-05-28 | — | — | US | disclosed |
| US-6121488-A | Quenching reagents for solution phase synthesis | WARNER-LAMBERT COMPANY (US) | 2000-09-19 | — | — | US | disclosed |