Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517647 | 0.78 | HTR6 (1.00) | HTR6HTR2C | |
| SCHEMBL21162354 | 0.76 | HTR6 (0.84) | HTR6HTR2C | |
| SCHEMBL21588295 | 0.76 | HTR6 (1.00) | HTR6HTR2C | |
| SCHEMBL6168803 | 0.74 | HTR6 (0.65) | HTR6HTR2C | |
| SCHEMBL6200394 | 0.70 | HTR6 (0.56) | HTR6HTR2C | |
| SCHEMBL6332768 | 0.70 | HTR6 (0.61) | HTR6 | |
| SCHEMBL3323737 | 0.70 | HTR6 (1.00) | HTR6 | |
| SCHEMBL1757851 | 0.69 | HTR6 (0.53) | HTR6 | |
| SCHEMBL6333362 | 0.68 | HDAC6 (0.66) | HTR6 | |
| SCHEMBL6197660 | 0.68 | HTR6 (0.52) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128475-A1 | 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position | PHARMACIA & UPJOHN COMPANY | 2002-09-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128475-A1 | 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position | HTR4, HTR3C, HTR3B | HTR6 17/4885HTR2C 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.