SCHEMBL7717191

SCHEMBL7717191

C=C(C)C(=O)OCCOC(C)OC(C)=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 6/20 0.48
ALDH1A1 P00352 3/20 0.36
GALR3 O60755 1/20 0.35
MAPT P10636 1/20 0.35
BLM P54132 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12101451 0.91 THRB (0.52) THRBTSHRALDH1A1TDP1POLB
SCHEMBL10350828 0.88 THRB (0.49) THRBTSHRALDH1A1TDP1POLB
SCHEMBL13943431 0.86 THRB (0.56) THRBTSHRALDH1A1TDP1POLB
SCHEMBL1323593 0.86 TSHR (0.44) THRBTSHRALDH1A1GALR3SMN1; SMN2
SCHEMBL18979685 0.84 TSHR (0.55) THRBTSHRALDH1A1TDP1POLB
SCHEMBL4863944 0.84 THRB (0.52) THRBTSHRALDH1A1TDP1POLB
SCHEMBL3267819 0.83 TSHR (0.47) THRBTSHRALDH1A1
SCHEMBL3387966 0.82 TSHR (0.50) TSHRALDH1A1GALR3MAPTBLM
SCHEMBL283500 0.82 THRB (0.59) THRBTSHRALDH1A1TDP1POLB
SCHEMBL5201539 0.81 THRB (0.53) THRBTSHRALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384146-B1 MIXING LIVING POLYMER WITH FIRST MONOMER UNDER CONDITIONS EFFECTIVE TO PRODUCE BLOCK COPOLYMER, MIXING BLOCK COPOLYMER WITH SECOND MONOMER UNDER CONDITIONS EFFECTIVE TO PRODUCE BLOCK-GRAFT OR STAR-SHAPED COPOLYMER THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2002-05-07 US claimed
US-8450393-B2 Polymeric compound containing composition, and image forming process and apparatus CANON KABUSHIKI KAISHA (JP) 2013-05-28 US disclosed
US-8450393-B2 Polymeric compound containing composition, and image forming process and apparatus CANON KABUSHIKI KAISHA (JP) 2013-05-28 US disclosed
US-20090311425-A1 POLYMERIC COMPOUND CONTAINING COMPOSITION, AND IMAGE FORMING PROCESS AND APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-12-17 US disclosed
US-6384146-B1 MIXING LIVING POLYMER WITH FIRST MONOMER UNDER CONDITIONS EFFECTIVE TO PRODUCE BLOCK COPOLYMER, MIXING BLOCK COPOLYMER WITH SECOND MONOMER UNDER CONDITIONS EFFECTIVE TO PRODUCE BLOCK-GRAFT OR STAR-SHAPED COPOLYMER THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2002-05-07 US disclosed
WO-2000059968-A9 GRAFT, GRAFT-BLOCK, BLOCK-GRAFT, AND STAR-SHAPED COPOLYMERS AND METHODS OF MAKING THEM UNIV NEW YORK STATE RES FOUND (US) 2002-02-21 WO disclosed
WO-2000059968-A1 GRAFT, GRAFT-BLOCK, BLOCK-GRAFT, AND STAR-SHAPED COPOLYMERS AND METHODS OF MAKING THEM THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2000-10-12 WO disclosed
US-4916197-A Hydrophilic copolymer and the method for producing thereof CESKOSLOVENSKA AKADEMIE VED (CS) 1990-04-10 US disclosed