Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.38 |
| ▸ | MBTPS1 | Q14703 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 4/20 | 0.34 |
| ▸ | FNTB | P49356 | 4/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7715398 | 1.00 | CYP11B1 (0.38) | CYP11B1CYP11B2MBTPS1KCNH2FNTA | |
| SCHEMBL7709318 | 0.83 | GPR119 (0.44) | KCNH2FNTAFNTBPGGT1BCACNA1H | |
| SCHEMBL7709319 | 0.83 | GPR119 (0.44) | KCNH2FNTAFNTBPGGT1BCACNA1H | |
| SCHEMBL7721388 | 0.78 | FNTA (0.44) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7721386 | 0.78 | FNTA (0.44) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7714120 | 0.71 | CYP11B1 (0.52) | CYP11B1CYP11B2FNTAFNTBPDPK1 | |
| SCHEMBL7713236 | 0.70 | CYP11B1 (0.70) | CYP11B1CYP11B2FNTAFNTBPGGT1B | |
| SCHEMBL7971164 | 0.69 | CYP11B1 (0.52) | CYP11B1CYP11B2CACNA1H | |
| SCHEMBL7709344 | 0.69 | CYP11B1 (0.51) | CYP11B1CYP11B2CACNA1H | |
| SCHEMBL7163804 | 0.68 | CYP11B1 (0.46) | CYP11B1CYP11B2KCNH2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441017-B1 | Inhibitors of prenyl-protein transferase | MERCK & CO., INC. | 2002-08-27 | — | — | US | disclosed |