Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 14/20 | 0.65 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718277 | 0.85 | PTGIR (0.89) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL8080971 | 0.85 | PTGIR (0.61) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7720284 | 0.80 | PTGIR (0.61) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL7779787 | 0.79 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7778581 | 0.75 | PTGIR (0.81) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL7716647 | 0.75 | PTGIR (0.50) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7717812 | 0.74 | PTGIR (0.44) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7779771 | 0.73 | PTGIR (0.46) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7776653 | 0.68 | PTGIR (0.81) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7718905 | 0.67 | PTGIR (0.65) | PTGIRPTGDRPTGER3PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384072-B1 | CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-1030834-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024397-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |