Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 18/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717821 | 0.85 | PTGIR (0.60) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL8068504 | 0.84 | BLM (0.54) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7718887 | 0.79 | PTGIR (0.40) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7779771 | 0.79 | PTGIR (0.46) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7778604 | 0.78 | PTGIR (0.64) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7778607 | 0.78 | PTGIR (0.64) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7778660 | 0.78 | PTGIR (0.64) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7713218 | 0.77 | PTGIR (0.63) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7720294 | 0.76 | PTGIR (0.54) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7717829 | 0.74 | PTGIR (0.65) | PTGIRPTGDRPTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384072-B1 | CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |