Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772410 | 0.86 | SIGMAR1 (0.52) | PTGIRSIGMAR1 | |
| SCHEMBL7778533 | 0.84 | PTGIR (0.67) | PTGIRPTGDRTBXAS1PTGER3PTGER1 | |
| SCHEMBL7772386 | 0.80 | PTGIR (0.54) | PTGIRSIGMAR1PTGDRTBXAS1PTGER3 | |
| SCHEMBL7717812 | 0.79 | PTGIR (0.44) | PTGIRPTGDRTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7713218 | 0.73 | PTGIR (0.63) | PTGIRPTGDRPTGER3PTGER1PTGER4 | |
| SCHEMBL7717829 | 0.73 | PTGIR (0.65) | PTGIRPTGDRTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5724520 | 0.70 | ESR1 (0.48) | SIGMAR1TAS1R3TAS1R1TAS1R2ESR1 | |
| SCHEMBL7776691 | 0.69 | ESR1 (0.53) | SIGMAR1TAS1R3TAS1R1TAS1R2ESR1 | |
| SCHEMBL9048482 | 0.69 | PTGIR (0.48) | PTGIRSIGMAR1 | |
| SCHEMBL8858400 | 0.69 | PTGIR (0.75) | PTGIRSIGMAR1PTGDRTBXAS1PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749424-B1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5863918-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5763489-A | ANTICOAGULANTS AND HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| WO-1995024393-A1 | NAPHTHALENE DERIVATIVES AS PROSTAGLANDIN I2 AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-14 | — | — | WO | disclosed |