Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24184143 | 0.76 | CRBN (0.35) | CRBNHSD17B10NPC1RAB9APKM | |
| SCHEMBL2266514 | 0.74 | — | — | |
| SCHEMBL7717839 | 0.74 | NPC1 (0.50) | CYP1A2CRBNHSD17B10NPC1RAB9A | |
| SCHEMBL2269416 | 0.73 | ALDH1A1 (0.36) | CYP1A2ALDH1A1KDM4E | |
| SCHEMBL7715691 | 0.72 | HPGD (0.41) | CYP1A2HSD17B10NPC1RAB9AGAA | |
| SCHEMBL21929908 | 0.71 | CRBN (0.36) | CRBNNPC1RAB9AKMT2APKM | |
| SCHEMBL15021064 | 0.71 | GPR84 (0.41) | KMT2AGPR84 | |
| SCHEMBL31001777 | 0.70 | CRBN (0.34) | CRBNNPC1RAB9A | |
| SCHEMBL2271845 | 0.70 | ALDH1A1 (0.38) | HSD17B10NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL24274526 | 0.69 | ADORA3 (0.46) | CYP1A2NPC1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-0888109-B1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-PYRIMIDINEOXO COMPOUNDS, USE THEREOF AS DYE COUPLERS, AND DYEING METHODS | OREAL (FR) | 2000-08-30 | — | — | EP | claimed |
| US-6379395-B1 | DYEING FOR HAIR DYE | L'OREAL S.A. (FR) | 2002-04-30 | — | — | US | disclosed |
| US-6179882-B1 | OXIDATION COLOR DYES | L'OREAL (FR) | 2001-01-30 | — | — | US | disclosed |