SCHEMBL7718147

SCHEMBL7718147

[CH]=CC1=COC(Cc2ccccc2)O1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.33
FASN P49327 1/20 0.32
GRM2 Q14416 1/20 0.30
GBA1 P04062 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490481 0.83 CTRB1 (0.36) CTRB1FASNGRM2
SCHEMBL5220133 0.76 HCAR2 (0.43)
SCHEMBL3744743 0.73 CTRB1 (0.35) CTRB1FASNGRM2GBA1
SCHEMBL746094 0.73 CTRB1 (0.35) CTRB1FASNGRM2GBA1
SCHEMBL5754991 0.73 TAAR1 (0.39) CTRB1FASNGRM2
SCHEMBL3972137 0.73 CTRB1 (0.35) CTRB1FASN
SCHEMBL16398868 0.71 TP53 (0.41) CTRB1FASN
SCHEMBL17512439 0.71 CALM1 (0.39) CTRB1FASNGRM2GBA1
SCHEMBL7593855 0.71 MAPT (0.40)
SCHEMBL7703226 0.70 KDM4E (0.35) CTRB1FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376548-B1 FUNGICIDES; HERBICIDES; INSECTICIDES ROHM AND HAAS COMPANY 2002-04-23 US disclosed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO disclosed