Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.66 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.65 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718270 | 1.00 | ALDH1A1 (0.69) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 | |
| SCHEMBL13766546 | 0.98 | TRIM24 (0.68) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 | |
| SCHEMBL9915657 | 0.90 | MAPT (0.65) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 | |
| SCHEMBL10770812 | 0.90 | MAPT (0.58) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 | |
| SCHEMBL10771126 | 0.89 | PTGS2 (0.59) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 | |
| SCHEMBL11589270 | 0.88 | MAPT (0.57) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 | |
| SCHEMBL11589274 | 0.88 | MAPT (0.57) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 | |
| SCHEMBL10772793 | 0.87 | MAPT (0.60) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 | |
| SCHEMBL1136730 | 0.87 | PTGS2 (0.62) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 | |
| SCHEMBL1136732 | 0.87 | PTGS2 (0.62) | ALDH1A1KDM4ESMN1; SMN2MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-20020185634-A1 | Two-photon or higher-order absorbing optical materials and methods of use | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-12-12 | — | — | US | disclosed |
| WO-1998021521-A9 | TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE | CALIFORNIA INST OF TECHN (US) | 2000-03-02 | — | — | WO | disclosed |
| WO-1998021521-A1 | TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-05-22 | — | — | WO | disclosed |