Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.55 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915631 | 0.92 | MAPT (0.73) | MAPTMITFALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7718270 | 0.90 | ALDH1A1 (0.69) | MAPTALDH1A1SMN1; SMN2KDM4EPTGS2 | |
| SCHEMBL7718267 | 0.90 | ALDH1A1 (0.69) | MAPTALDH1A1SMN1; SMN2KDM4EPTGS2 | |
| SCHEMBL6245150 | 0.88 | LMNA (0.60) | MAPTALDH1A1SMN1; SMN2KDM4ETRIM24 | |
| SCHEMBL9092806 | 0.88 | LMNA (0.60) | MAPTALDH1A1SMN1; SMN2KDM4ETRIM24 | |
| SCHEMBL13766546 | 0.88 | TRIM24 (0.68) | MAPTALDH1A1SMN1; SMN2KDM4EPTGS2 | |
| SCHEMBL2175616 | 0.85 | LMNA (0.62) | MAPTALDH1A1SMN1; SMN2KDM4ETRIM24 | |
| SCHEMBL29013980 | 0.85 | MAPT (0.65) | MAPTMITFALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL2604938 | 0.85 | MAPT (0.65) | MAPTMITFALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1124042 | 0.82 | CTSK (0.52) | MAPTMITFALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |