Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.42 |
| ▸ | TDO2 | P48775 | 8/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28431726 | 0.85 | IDO1 (0.40) | IDO1TDO2HTTTSHRSCN1A | |
| SCHEMBL2510268 | 0.80 | HTT (0.40) | IDO1TDO2HTTTSHRSCN1A | |
| SCHEMBL2839765 | 0.79 | HTT (0.41) | IDO1TDO2HTTDPP4TSHR | |
| SCHEMBL7716632 | 0.79 | HTT (0.41) | IDO1TDO2HTTDPP4TSHR | |
| SCHEMBL127629 | 0.73 | IDO1 (0.46) | IDO1TDO2HTTDPP4TSHR | |
| SCHEMBL27280965 | 0.73 | IDO1 (0.46) | IDO1TDO2HTTDPP4TSHR | |
| SCHEMBL2512456 | 0.72 | IDO1 (0.34) | IDO1TDO2HTTTSHRF2 | |
| SCHEMBL15803228 | 0.72 | IDO1 (0.38) | IDO1TDO2HTTTSHRSCN1A | |
| SCHEMBL11034847 | 0.71 | IDO1 (0.41) | IDO1TDO2HTTTSHRSCN1A | |
| SCHEMBL15052233 | 0.71 | IDO1 (0.37) | IDO1TDO2HTTTSHRSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | claimed |
| US-6376615-B1 | USING FREE RADICALS | CENTRO DE INVESTIGACION EN QUIMICA APLICADA (MX) | 2002-04-23 | — | — | US | disclosed |