Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 6/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54603 | 0.87 | CA2 (0.35) | CYP19A1CA1CA2CA9CA12 | |
| SCHEMBL23779534 | 0.79 | MAOB (0.52) | MAOBMAOACYP19A1CA1CA2 | |
| SCHEMBL29634429 | 0.79 | MAOB (0.52) | MAOBMAOACYP19A1CA1CA2 | |
| SCHEMBL7721269 | 0.79 | KMT2A (0.44) | MAOBMAOAALDH1A1TDP1 | |
| SCHEMBL15567377 | 0.79 | TAAR1 (0.43) | MAOBMAOAALDH1A1HSD17B10LMNA | |
| SCHEMBL589307 | 0.77 | MAOB (0.50) | MAOBMAOACYP19A1CA1CA2 | |
| SCHEMBL6401924 | 0.77 | ALDH1A1 (0.53) | MAOBMAOACYP19A1CA1CA2 | |
| SCHEMBL7716393 | 0.77 | RECQL (0.42) | MAOBMAOACA1CA2CA9 | |
| SCHEMBL2464599 | 0.77 | CA1 (0.59) | MAOBMAOACYP19A1CA1CA2 | |
| SCHEMBL30279898 | 0.77 | MAOB (0.50) | MAOBMAOACYP19A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376656-B1 | DISAZO DYES, TRIAZINE DYES | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-04-23 | — | — | US | disclosed |
| CN-1067419-C | Reactive dyestuffs their preparation and their use | BAYER AG (DE) | 2001-06-20 | — | — | CN | disclosed |
| EP-0652262-B1 | Reactive dyestuffs, their preparation and use | BAYER AG (DE) | 2000-07-12 | — | — | EP | disclosed |
| US-6025478-A | HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS | BAYER AG (DE) | 2000-02-15 | — | — | US | disclosed |
| EP-0641838-B1 | Reactive dye-stuffs on basis of a substituted barbituric acid | BAYER AG (DE) | 1999-11-10 | — | — | EP | disclosed |
| EP-0568876-B1 | Reactive dyes, their preparation and their use | BAYER AG (DE) | 1996-08-28 | — | — | EP | disclosed |
| US-5502174-A | Reactive dyestuffs based on a substituted barbituric acid | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| CN-1106845-A | Reactive dyestuffs their preparation and their use | BAYER AG (DE) | 1995-08-16 | — | — | CN | disclosed |
| EP-0652262-A1 | Reactive dyestuffs, their preparation and use | BAYER AG (DE) | 1995-05-10 | — | — | EP | disclosed |
| EP-0641838-A1 | Reactive dye-stuffs on basis of a substituted barbituric acid | BAYER AG (DE) | 1995-03-08 | — | — | EP | disclosed |
| EP-0568876-A1 | Reactive dyes, their preparation and their use | BAYER AG (DE) | 1993-11-10 | — | — | EP | disclosed |
| US-5166338-A | Dioxazine or phthalocyanine dyes for wool or cellulose | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |