Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.69 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.69 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.69 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.69 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | PRKACA | P17612 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vk-19911 SCHEMBL140202 | 0.82 | MAPK14 (1.00) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL4098093 | 0.79 | MAPK14 (0.71) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL7722180 | 0.79 | MAPK14 (0.53) | MAPK14MAPK11MAPK13MAPK12BRDT | |
| SCHEMBL29135093 | 0.74 | MAPK14 (0.40) | MAPK14MAPK11MAPK13MAPK12CSNK1D | |
| SCHEMBL4910253 | 0.73 | MAPK14 (1.00) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL7688265 | 0.73 | MAPK14 (0.45) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL7688263 | 0.72 | MAPK14 (0.42) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL1639811 | 0.71 | MAPK14 (0.58) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL27984882 | 0.70 | MAPK14 (0.57) | MAPK14MAPK11MAPK13MAPK12PRKD3 | |
| SCHEMBL19864314 | 0.69 | MAPK14 (0.90) | MAPK14MAPK11MAPK13MAPK12PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387898-B1 | USING IMIDAZOLE COMPOUND | SMITHKLINE BEECHAM CORPORATION | 2002-05-14 | — | — | US | disclosed |