SCHEMBL7720231

SCHEMBL7720231

CC1(COc2ccc(S(=O)(=O)c3ccc(O)cc3)cc2)CO1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 5/20 0.51
GAA P10253 3/20 0.51
ELANE P08246 2/20 0.46
ALDH1A1 P00352 3/20 0.43
LMNA P02545 2/20 0.43
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP7 P09237 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
MMP14 P50281 1/20 0.36
ENPP2 Q13822 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LTA4H P09960 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31349 0.84 CA12 (0.52) MMP2MMP9MMP14CA12CA1
SCHEMBL6301749 0.84 MAOB (0.48) ALDH1A1MAPTMMP9CA12CA1
SCHEMBL8611881 0.83 PKM (0.49) PKMGAAALDH1A1POLBMAPT
SCHEMBL6295731 0.80 KMT2A (0.44) PKMGAAALDH1A1POLBMAPT
SCHEMBL6694113 0.78 HPGD (0.47) ALDH1A1LMNAPOLBMAPTKMT2A
SCHEMBL8614904 0.78 PKM (0.41) PKMGAAALDH1A1LMNAPOLB
SCHEMBL1144646 0.77 CA12 (0.45) LMNACA12CA1CA2CA9
SCHEMBL8611561 0.76 HSD11B1 (0.44) GAAALDH1A1LMNAPOLBMAPT
SCHEMBL5707066 0.76 CA12 (0.43) LMNAMAPTCA12CA1CA2
SCHEMBL417833 0.75 GAA (0.65) PKMGAAELANEALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764635-B1 DIPHENYL SULFONE DERIVATIVE AND RECORDING MATERIAL PREPARED THEREFROM NIPPON SODA CO (JP) 2002-03-27 EP disclosed
US-6143060-A EXCELLENT IN THE STORAGE STABILITY OF DEVELOPED IMAGES, PARTICULARLY THE RESISTANCE THEREOF TO PLASTICIZERS NIPPON SODA CO., LTD. (JP) 2000-11-07 US disclosed
US-6103661-A Diphenyl sulfone derivative and recording material prepared therefrom NIPPON SODA CO., LTD. (JP) 2000-08-15 US disclosed
EP-0906908-A1 TRIAZINE DERIVATIVES AND RECORDING MATERIALS PREPARED THEREFROM NIPPON SODA CO., LTD. (JP) 1999-04-07 EP disclosed
US-5801288-A Diphenyl sulfone derivative and recording material prepared therefrom NIPPON SODA CO., LTD. (JP) 1998-09-01 US disclosed
EP-0764635-A1 DIPHENYL SULFONE DERIVATIVE AND RECORDING MATERIAL PREPARED THEREFROM NIPPON SODA CO., LTD. (JP) 1997-03-26 EP disclosed
EP-0623594-B1 PHENETHYL ALCOHOL DERIVATIVE AND RECORDING MATERIAL CONTAINING THE SAME NIPPON SODA CO (JP) 1996-12-27 EP disclosed
US-5463133-A Stabilizing agent for colored images, color developer NIPPON SODA CO., LTD. (JP) 1995-10-31 US disclosed
EP-0623594-A1 PHENETHYL ALCOHOL DERIVATIVE AND RECORDING MATERIAL CONTAINING THE SAME NIPPON SODA CO., LTD. (JP) 1994-11-09 EP disclosed