Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 7/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | DRD1 | P21728 | 4/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081130 | 0.86 | PTGIR (0.49) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7777424 | 0.85 | PTGIR (0.72) | PTGIRPTGDRCA1CA2ACHE | |
| SCHEMBL7716590 | 0.85 | PTGIR (0.77) | PTGIRPTGDRPTGER3PTGER1 | |
| SCHEMBL7713218 | 0.81 | PTGIR (0.63) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7718288 | 0.79 | PTGIR (0.51) | PTGIRPTGDRCA1CA2ACHE | |
| SCHEMBL7717812 | 0.76 | PTGIR (0.44) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7716647 | 0.74 | PTGIR (0.50) | PTGIRPTGDRCA1CA2ACHE | |
| SCHEMBL7779671 | 0.72 | PTGIR (0.77) | PTGIRPTGDRCA1CA2ACHE | |
| SCHEMBL8068504 | 0.70 | BLM (0.54) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7772466 | 0.70 | PTGIR (1.00) | PTGIRPTGDRPTGER3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384072-B1 | CARBAMYL SUBSTITUTED COMPOUNDS WITH ETHER GROUPS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |