Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PTGIR | P43119 | 15/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717812 | 0.84 | PTGIR (0.44) | BLMPTGIRPTGDRPTGER4PTGER3 | |
| SCHEMBL7717821 | 0.80 | PTGIR (0.60) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL8081130 | 0.76 | PTGIR (0.49) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7718887 | 0.75 | PTGIR (0.40) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7778660 | 0.75 | PTGIR (0.64) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7778607 | 0.75 | PTGIR (0.64) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7778604 | 0.75 | PTGIR (0.64) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL8080971 | 0.72 | PTGIR (0.61) | BLMTSHRPTGIRPTGDRPTGER4 | |
| SCHEMBL7778572 | 0.71 | PTGIR (0.52) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL7776682 | 0.71 | PTGIR (0.52) | PTGIRPTGDRPTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030834-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024397-A1 | BENZOCYCLOHEPTENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-05-20 | — | — | WO | disclosed |