Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717160 | 0.86 | — | — | |
| SCHEMBL7718536 | 0.77 | — | — | |
| SCHEMBL510134 | 0.75 | SLC6A2 (0.39) | SLC6A2SLC6A4OPRD1CYP2D6SLC6A3 | |
| SCHEMBL6556075 | 0.75 | SLC6A4 (0.36) | SLC6A2SLC6A4OPRD1CYP2D6KCNH2 | |
| SCHEMBL7719093 | 0.75 | FDPS (0.31) | — | |
| SCHEMBL5066970 | 0.73 | SLC6A4 (0.35) | SLC6A2SLC6A4OPRD1CYP2D6KCNH2 | |
| SCHEMBL2551138 | 0.73 | KDM4E (0.37) | SLC6A2SLC6A4OPRD1CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL4386425 | 0.73 | SLC6A2 (0.38) | SLC6A2SLC6A4OPRD1CYP2D6KCNH2 | |
| SCHEMBL13419180 | 0.73 | KDM4E (0.37) | SLC6A2SLC6A4OPRD1CYP2D6KCNH2 | |
| SCHEMBL5605219 | 0.73 | OPRD1 (0.37) | SLC6A2SLC6A4OPRD1CYP2D6SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002087587-A2 | 4-AMINOSULFONYLQUINAZOLINES AND -QUINOLINES AS TYROSINE KINASE INHIBITORS | CELLTECH R & D LIMITED (GB) | 2002-11-07 | — | — | WO | disclosed |