SCHEMBL510134

SCHEMBL510134

CCC(CC)N1CCNCC1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.39
SLC6A4 P31645 4/20 0.39
SLC6A3 Q01959 1/20 0.39
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TP53 P04637 1/20 0.35
OPRD1 P41143 2/20 0.35
HRH3 Q9Y5N1 8/20 0.34
CYP2D6 P10635 1/20 0.33
CYP19A1 P11511 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4386425 0.97 SLC6A2 (0.38) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL29031903 0.91 SIGMAR1 (0.36) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL11344053 0.86 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL23956553 0.86 SLC6A4 (0.39) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL4534735 0.86 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL3301449 0.85 KDM4E (0.31) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
Hydrochloric Acid SCHEMBL6956663 0.84 SLC6A2 (0.34) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL11122182 0.83 SLC6A4 (0.37) SLC6A2SLC6A4SLC6A3KDM4EALDH1A1
SCHEMBL26760915 0.83 SIGMAR1 (0.43) SLC6A2SLC6A4SLC6A3ALDH1A1OPRD1
SCHEMBL9821152 0.81 POLB (0.38) SLC6A2SLC6A4SLC6A3OPRD1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11787785-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2023-10-17 US claimed
US-20230108325-A1 Pyrazolopyridine Derivatives and Uses thereof NOVARTIS AG (CH) 2023-04-06 US claimed
US-20140273458-A1 Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-18 US claimed
EP-2779217-A2 Chemical mechanical planarization for tungsten-containing substrates AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-09-17 EP claimed
CN-104046246-A Chemical Mechanical Planarization for Tungsten-Containing Substrates AIR PROD & CHEM 2014-09-17 CN claimed
US-12503439-B2 Heteroaryl compounds for the treatment of pain VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-12-23 US disclosed
CN-119143715-B Diaryl methylpiperazine compound and preparation method, pharmaceutical composition and application thereof 天津匠新致成科技有限公司 2025-03-14 CN disclosed
CN-119143715-A Diaryl methylpiperazine compound and preparation method, pharmaceutical composition and application thereof 天津匠新致成科技有限公司 2024-12-17 CN disclosed
US-20230373925-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN VERTEX PHARMACEUTICALS INCORPORATED 2023-11-23 US disclosed
US-11820767-B2 Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection UNIVERSITY OF NOTRE DAME DU LAC (US) 2023-11-21 US disclosed
US-11820767-B2 Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection UNIVERSITY OF NOTRE DAME DU LAC (US) 2023-11-21 US disclosed
US-11787785-B2 Pyrazolopyridine derivatives and uses thereof NOVARTIS AG (CH) 2023-10-17 US disclosed
US-20040019039-A1 Substituted piperazines and diazepanes HIGH POINT PHARMACEUTICALS, LLC 2004-01-29 US disclosed
US-20030236259-A1 Novel aryl- and heteroarylpiperazines HIGH POINT PHARMACEUTICALS, LLC 2003-12-25 US disclosed
US-20030166644-A1 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase NOVO NORDISK A/S (DK) 2003-09-04 US disclosed
US-20030166690-A1 Use of compounds for decreasing activity of hormone-sensitive NOVO NORDISK A/S (DK) 2003-09-04 US disclosed
WO-2003066604-A2 NOVEL ARYL- AND HETEROARYLPIPERAZINES NOVO NORDISK A/S (DK) 2003-08-14 WO disclosed
WO-2003051842-A2 COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed
WO-2003051841-A2 COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE NOVO NORDISK A/S (DK) 2003-06-26 WO disclosed
WO-2003004480-A2 SUBSTITUTED PIPERAZINE AND DIAZEPANES AS HISTAMINE H3 RECEPTOR AGONISTS NOVO NORDISK A/S (DK) 2003-01-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820767-B2 Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection BET1, BRD4, BRD3 SLC6A2 3665/4885SLC6A4 4500/4885SLC6A3 3602/4885
US-11787785-B2 Pyrazolopyridine derivatives and uses thereof HBZ, ZFX, WIZ SLC6A2 4268/4885SLC6A4 3594/4885SLC6A3 3280/4885
US-20230373925-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN TRPV1, SCN3A, KCNN3 SLC6A2 204/4885SLC6A4 197/4885SLC6A3 230/4885
US-20030236259-A1 Novel aryl- and heteroarylpiperazines HRH3, HRH2, HRH4 SLC6A2 788/4885SLC6A4 1848/4885SLC6A3 1371/4885
US-20030166644-A1 Compounds and uses thereof for decreasing activity of hormone-sensitive lipase LIPE, PNLIP, LPL SLC6A2 4622/4885SLC6A4 4673/4885SLC6A3 4329/4885
US-12503439-B2 Heteroaryl compounds for the treatment of pain TRPV1, SCN3A, KCNN3 SLC6A2 204/4885SLC6A4 197/4885SLC6A3 230/4885
US-20030166690-A1 Use of compounds for decreasing activity of hormone-sensitive LIPE, PNLIP, LPL SLC6A2 4264/4885SLC6A4 4366/4885SLC6A3 3627/4885
US-20040019039-A1 Substituted piperazines and diazepanes HRH3, HRH4, HRH1 SLC6A2 974/4885SLC6A4 858/4885SLC6A3 652/4885
US-20230108325-A1 Pyrazolopyridine Derivatives and Uses thereof HBZ, ZFX, WIZ SLC6A2 4268/4885SLC6A4 3594/4885SLC6A3 3280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.