SCHEMBL7720740

SCHEMBL7720740

CCC(=O)C(=O)Oc1ccc(S(=O)(=O)C(=[N+]=[N-])S(C)(=O)=O)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
PTGS2 P35354 2/20 0.35
ELANE P08246 3/20 0.34
KMT2A Q03164 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
ESR1 P03372 2/20 0.32
HIF1A Q16665 2/20 0.32
RECQL P46063 1/20 0.32
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA7 P43166 2/20 0.31
CA9 Q16790 2/20 0.31
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
PRTN3 P24158 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7724564 0.83 MAPT (0.56) POLBMAPTPKMPTGS2ELANE
SCHEMBL7722372 0.80 KMT2A (0.49) POLBMAPTPKMPTGS2ELANE
SCHEMBL7717464 0.80 ELANE (0.46) POLBMAPTPKMPTGS2ELANE
SCHEMBL7691181 0.79 MMP2 (0.43) SMN1; SMN2CA12CA1CA2CA7
SCHEMBL7694841 0.77 MMP2 (0.40) POLBMAPTPKMGAACA12
SCHEMBL7724562 0.76 KMT2A (0.51) POLBMAPTPKMELANEKMT2A
SCHEMBL6735762 0.76 TSHR (0.50) RECQLCA12CA1CA2CA7
SCHEMBL6736840 0.76 TSHR (0.50) RECQLCA12CA1CA2CA7
SCHEMBL7724577 0.76 ELANE (0.51) POLBMAPTPKMPTGS2ELANE
SCHEMBL7721693 0.75 KMT2A (0.39) POLBMAPTELANEKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395446-B1 CONTAINING SULFONYLDIAZOMETHANE COMPOUND AS ACID GENERATOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-05-28 US disclosed